If you continue to experience issues after attempting all solutions, contact Epson technical support directly, providing them with your printer model, Windows version (e.g., Windows 11 Pro 64-bit), and the exact error message text. They can supply specialized diagnostic tools or updated drivers specific to your hardware revision.
The Windows Registry contains entries pointing to the location of Epr.dll 64 . If these registry keys become corrupted—due to improper uninstalls or malware—the system cannot locate the file even if it physically exists.
Run a full scan with Windows Defender or Malwarebytes.
Are you seeing this error specifically when trying to or when launching a specific application ?