The epsxe000.mcr file is the digital heartbeat of your PS1 nostalgia. It holds the hours of grinding, the boss defeats, and the unlocked secrets of your favorite 32-bit classics. By knowing where it is and how to back it up, you ensure that your gaming history remains safe from technical glitches.

Yes, as long as you point ePSXe to the new file in the memory card configuration.

If you are having trouble getting your saves to appear, consider these common configuration steps found on community forums like NGEmu :